Topics
Cell Migration
- How do cells coordinate shape change during migration?
- Where and how do cells generate various modes of mechanical forces during cell migration?
- How do cells regulate the assembly and disassembly of cytoskeletonl and adhesion structures during migration?
- How do cells migrate in a 3D environment?
Cell Division
- How are mechanical forces distributed and regulated across the cell cortex during cell division?
- What are the roles of chromosomes and spindle poles in regulating cortical ingression?
- What are the functional roles of different sets of microtubules in cytokinesis?
- How do microtubules interact with the cell cortex during cytokinesis?
Mechano and Geometric Sensing
- How do cells detect and respond to mechanical forces?
- How do cells detect and respond to substrate rigidity?
- How do cells respond to substrate geometry and topography?
Imaging and Image Processing
- Technology for detecting structural interactions and movements in living cells.
- Technology for detecting mechanical interactions in living cells.
- Technology for extracting information from cell images of limited S/N.
